Life-Saving Naloxone Delivered

An opioid overdose can happen at any time to anyone taking opioid medications or illicit drugs containing opioids. At CompreCareRx, we believe each and every patient, friend, family member or caregiver should be ready with accessible naloxone in order to reverse an opioid overdose and save a life. Now you can order this life-saving medication online.

Naloxone, also known as Narcan®, is available without a prescription in most states that CompreCareRx ships to:

What to do in an emergency.

If you or your loved one are experiencing any of the following call 911 immediately:

  • a medical emergency
  • a suspected overdose
  • at risk of severe harm to self or others
  • trouble breathing or other respiratory issues

If you or your loved one are experiencing a suspected opioid overdose and have naloxone (Narcan) available, call 911 immediately and then administer the naloxone to the person following all manufacturer instructions for safe use. A second dose may be required if the person is still unresponsive after 2-3 minutes. Note that effects of naloxone are temporary and immediate medical attention is necessary. Calling 911 is always the first course of action.

Click For More Info on Overdose Response

If you, or someone you know, is in need of treatment for Opioid Use Disorder visit to learn about Medication-Assisted Treatment at home.

Naloxone is covered by most insurances, and can be purchased with HSA, FSA, and pharmacy discount cards.

We have doctors that can write the script quickly and easily.

Narcan Nasal Spray


Naloxone Nasal Spray Kit (Luer–Jet)


1How can I get Naloxone without a prescription?

Don’t have a prescription for Naloxone? Most states have made Naloxone available without a written prescription from a prescriber.

Once your order is placed, our pharmacists will contact you to provide you with necessary instruction and counseling.

Your order will also contain instructions on how to recognize an opioid overdose and how to use naloxone.

Shipping Locations:
Arizona, Connecticut, Florida, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Maine, Massachusetts, Michigan, Missouri, New Hampshire,
New York, Ohio, Pennsylvania, South Carolina, Tennessee, Utah, Vermont, Virginia, Washington DC, and West Virginia.

2What is Naloxone?

Naloxone is the primary reversal agent for opioid medications.

It is often described as an opioid antagonist because it competes with opioid medications, thereby reversing their effect. Naloxone is indicated for emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression or unconsciousness.

3Who is at risk for an overdose?

The World Health Organization (WHO) identify the following risk factors for opioid overdose:

  • People who use prescription opioids, in particular those taking higher doses (≥50 morphine milligram equivalents [MME])
  • People who use opioids in combination with other sedating substances, such as benzodiazepines
    • People who use opioids and have medical conditions such as HIV, liver or lung disease, or suffer from depression
    • Household members of people in possession of opioids (including prescription opioids)
    • People with opioid dependence, in particular following reduced tolerance (following detoxification, release from incarceration, cessation of treatment)
    • People who inject opioids

Sources: Information Sheet on Opioid Overdose and CDC Guideline for Prescribing Opioids for Chronic Pain.

4Can I purchase Naloxone for a family member or friend?


Naloxone can be purchased for loved ones and others. Simply contact us at 1-888-644-8326 or and a member of our team can assist you.

5What states can CompreCare ship Naloxone to?

Shipping Locations:
Arizona, Connecticut, Florida, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Maine, Massachusetts, Michigan, Missouri, New Hampshire,
New York, Ohio, Pennsylvania, South Carolina, Tennessee, Utah, Vermont, Virginia, Washington DC, and West Virginia.

6Can you abuse Naloxone?

Naloxone cannot be abused.

It is used as a reversal agent caused by accidental opioid overdose.

7What if I have other questions about ordering or shipping?

Other questions and answers can be found on the "For Patients" page of the website. You can also click this link to go there directly.

You can always contact us directly at at 1-888-644-8326 or email us at if you have other specific questions as well.

How to respond to an overdose using naloxone

Steps to identify and act on an opioid overdose:

Step 1: Identify the overdose and check responsiveness

Opioids can suppress breathing. If someone is not breathing or is struggling to breathe, try calling the person's name and rubbing your knuckles on their chest. If there's still no response, they could be experiencing an overdose.

Signs of overdose:

  • blue or pale skin color
  • small pinpoint pupils
  • low blood pressure
  • slow heartbeat
  • slow or shallow breathing
  • snoring sound
  • gasping for air

Step 2: Get help and Call 9-1-1

After identifying an overdose, call for help as quickly as possible. Call 9-1-1. Make sure to say the person is unresponsive and not breathing or struggling to breathe. Give a clear address and location of where you are.

Step 3: Perform Rescue Breathing

Giving oxygen can save someone experiencing an overdose. Perform basic CPR (Cardiopulmonary Resuscitation):

  1. Make sure nothing is in the person's mouth that can block breathing.
  2. Place one hand on the person's chin and tilt head back. Pinch their nose closed with the other hand.
  3. Administer 2 slow breaths and look for the person's chest to rise.
  4. Continue administering 1 breath every 5 seconds until the person starts breathing on their own.
  5. If the person is still unresponsive after repeating for 30 seconds, you can give naloxone.

Step 4: Administer naloxone

Follow the instructions for the form of naloxone you have - injectable or nasal spray. Don't forget to give rescue breaths while you prepare to administer naloxone.

After administering naloxone, continue giving rescue breaths, 1 breath every 5 seconds. If the person is still unresponsive in 2 to 3 minutes, you can give a second dose of naloxone. Continue breaths until emergency responders arrive.

Click for Narcan Manufacturer Instructions for Use
Click for Generic Naloxone Nasal Spray Directions for Use

Step 5: Stay until help arrives

Stay to make sure the person:

  • Doesn't go into withdrawal
  • Doesn't take more opioids, which could send them back into overdose
  • Doesn't go back into overdose and need additional doses of naloxone
  • Doesn't experience rapid or irregular heartbeat, chest pain, seizures, sudden stopping of the heart, hallucinations or loss of consciousness, all of which require immediate medical attention

1. World Health Organization. Information Sheet on Opioid Overdose. Available at:
2. Centers for Disease Control and Prevention. Guideline for prescribing opioids for chronic pain. Available at:
3. West Virginia Department of Health and Human Resources

Reference: West Virginia Department of Health and Human Resources

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